It is supposed to be stand-alone subgame, like Sub0, SubFLF and Sub32.
I hope its story will fix some black holes in general plotline of Submachine.

If Murtaugh made the karma stabilizer after meeting the player, why the player has been able to use it? And how has he learned the story of the karma stabilizer through the notes in Sub10 if the story still hasn't happened?At one of these meetings she (Liz) and Murtaugh met the player (referring to Sub10's ending at the desert).
Murtaugh eventually succeeded in making a karma stabiliser to restore karma portals to their original state. After dying shortly afterwards, Elizabeth spread his knowledge of karma to anyone she could reach. Elizabeth eventually died as well and was buried in the temple, alongside Murtaugh, where she is believed to reside in the light of Shiva.
why not, if there's time travel involved? it's a form of retrocausality.you can only see the changes you made in the past after having made it in the same timeline, you can't be at a present time and see it already changed before you change it.